Buy Kisspeptin-10

Buy Kisspeptin -10, a synthetic decapeptide (Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂) corresponding to the C-terminal active fragment of the KISS1 gene product. Studied for activation of the KISS1R (GPR54) receptor and its role in gonadotropin-releasing hormone signaling in reproductive-endocrinology research. 10mg lyophilized powder, 99%+ purity verified by Janoshik Analytical via HPLC and mass spectrometry.

• For laboratory research use only.

• Not for human or veterinary use.

• Not intended for diagnosis, treatment, cure, or prevention of any disease.

• Use only in controlled laboratory settings by qualified personnel following appropriate safety procedures.

Kisspeptin-10 (KP-10) is the shortest fully active fragment of kisspeptin, a neuropeptide encoded by the KISS1 gene and cleaved from the 54-amino-acid precursor metastin. Acting on the G-protein-coupled receptor KISS1R (formerly GPR54), kisspeptin is a primary upstream regulator of GnRH neurons and is therefore a central tool in research on the hypothalamic–pituitary–gonadal axis. Its compact decapeptide structure retains the full receptor-binding activity of the longer parent peptides.

BENEFITS/Buy Kisspeptin

• GnRH signaling — studied for upstream stimulation of gonadotropin-releasing hormone neurons

• KISS1R activation — investigated for agonist activity at the GPR54 receptor

• Reproductive endocrinology — explored as a tool in hypothalamic–pituitary–gonadal axis research

• Compact active fragment — retains full receptor activity of the parent kisspeptin

• Well-defined target — extensively characterized KISS1R research ligand

WHAT RESEARCHERS LOOK AT

• KISS1R (GPR54) receptor binding and downstream signaling

• Regulation of GnRH neuron activity and gonadotropin (LH/FSH) release

• Hypothalamic–pituitary–gonadal axis research models

• Pulsatile versus continuous exposure signaling dynamics

• Structure–activity relationships of the C-terminal decapeptide

QUICK SPECS

• Form: Lyophilized peptide

• Net per vial: 10 mg

• Purity: ≥99% (HPLC verified)

• Identity: MS-verified (per COA)

• Storage: 2–8°C short-term, -20°C long-term, protect from light and moisture

• Reconstitution: Use bacteriostatic water (sold separately)

IDENTITY BASICS

• Sequence: Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂ (decapeptide)

• Molecular Formula: C₆₃H₈₃N₁₇O₁₄

• Molecular Weight: 1302.45 g/mol

• CAS Number: 374675-21-5

• Common Synonyms: KP-10, Kisspeptin-112–121, Metastin (45–54)