MOTS-c – 40mg

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA Type-c), a mitochondrial-derived peptide studied for AMPK activation, metabolic regulation, and exercise mimetic pathways. 40mg lyophilized powder, 99%+ purity verified by Janoshik Analytical via HPLC and mass spectrometry.

• For laboratory research use only.

• Not for human or veterinary use.

• Not intended for diagnosis, treatment, cure, or prevention of any disease.

• Use only in controlled laboratory settings by qualified personnel following appropriate safety procedures.

MOTS-c has been widely discussed in metabolic and exercise science communities for its role in energy metabolism and cellular aging research. It is frequently mentioned alongside other longevity interventions in biohacking circles focused on healthspan extension.

BENEFITS/MOTS-c

• Metabolic regulation — studied for activating AMPK and improving glucose uptake

• Exercise mimetic — explored as a potential exercise-signaling molecule

• Mitochondrial function — linked to mitochondrial biogenesis and energy production

• Longevity — associated with healthspan extension in aging models

• Insulin sensitivity — investigated for effects on metabolic homeostasis

WHAT RESEARCHERS LOOK AT

• AMPK activation and downstream metabolic signaling

• Mitochondrial-derived peptide biology and mitochondrial DNA encoding

• Exercise mimetic properties and skeletal muscle metabolism

• Age-related decline of endogenous MOTS-c levels

• Insulin sensitivity and glucose regulation pathways

• Comparative analysis with other mitochondrial-derived peptides (Humanin, SHLP)

QUICK SPECS

• Form: Lyophilized peptide powder

• Net per vial: 40 mg

• Purity: ≥99% (HPLC verified)

• Identity: MS-verified (per COA)

• Storage: 2–8°C, protect from light and moisture

• Reconstitution: Use bacteriostatic water (sold separately)

IDENTITY BASICS

• Sequence: MRWQEMGYIFYPRKLR

• Molecular Weight: 2174.69 g/mol

• CAS: 1627580-64-6

• Classification: Mitochondrial-derived peptide